Are organoids suitable for human disease research?
Yes. Organoids are highly suitable for studying a broad range of human diseases, including cancer, monogenic genetic disorders, and metabolic diseases. They faithfully recapitulate patient-specific pathological features and tissue architecture, serving as powerful tools for disease mechanism exploration and personalized drug screening. However, limitations exist such as insufficient vascularization and incomplete immune/stromal cell integration, restricting their application in systemic disease modeling.