Bovine Liver Organoid
Bovine liver organoids originate from cattle hepatic stem/progenitor cells and maintain the cellular diversity of bovine hepatic epithelium, encompassing hepatocytes and cholangiocytes while reconstituting the urea cycle, carbohydrate/lipid metabolism, and xenobiotic metabolism. Research applications include ruminant liver pathophysiology, monitoring of antibiotic and veterinary-drug residues, and evaluation of nutrition-related metabolism and production traits. Organoids can be cryopreserved in FBS/DMSO/Y-27632 freezing medium and efficiently revived after long-term storage. All batches are cleared by mycoplasma/bacterial/fungal testing and confirmed for identity and genetic stability (e.g., lineage markers, species-specific PCR or STR, karyotype/sequencing) with release based on functional metrics such as albumin secretion, urea production, and CYP induction.
Specifications
- cat no
- C-053
- disease
- Normal
- organism
- Bovine
- tissue
- Liver
- growth properties
- Embedded 3D Culture
- biosafety level
- 1
- growth conditions
- 37℃, 95% Air, 5% CO 2
- size quantity
- 1
- product format
- Frozen
- shipping info
- Dry Ice
- storage conditions
- Liquid Nitrogen
- quality control
- All test negative for mycoplasma, bacteria, yeast, and fungi.
- application
- For research use only. Tissue-derived organoids are widely used in drug screening, disease modeling, mechanism research, personalized medicine, and regenerative medicine. By simulating authentic disease states, these organoids provide an ideal platform to assess patient responses to new drugs and assist in the design of personalized treatment plans. Additionally, they drive the development of new therapeutic approaches, particularly in cancer research and organ regeneration, offering precise experimental tools that greatly enhance the advancement of precision medicine.