C-020
Human Familial Adenomatous Polyposis (FAP) Normal Duodenum Organoid
Human Familial Adenomatous Polyposis (FAP) Normal Duodenum Organoid are derived from biopsies of histologically normal duodenal mucosa, and they recapitulate the structure and function of the normal intestinal epithelium. The cell composition and arrangement of the epithelium make intestinal organoids useful for studying intestinal cell biology, regeneration, differentiation, as well as disease phenotypes including effects of specific mutations, microbiome, or inflammation processes. Organoids are rigorously tested for mycoplasma, bacteria, fungi/yeast, and verified for identity, genetic stability, and functional performance.
Specifications
- cat no
- C-020
- disease
- Normal
- organism
- Human
- tissue
- Duodenum
- growth properties
- Embedded 3D Culture
- biosafety level
- 1
- growth conditions
- 37℃, 95% Air, 5% CO 2
- size quantity
- 1
- product format
- Frozen
- shipping info
- Dry Ice
- storage conditions
- Liquid Nitrogen
- quality control
- All test negative for mycoplasma, bacteria, yeast, and fungi.
- application
- For research use only. Organoid model enables studies of intestinal epithelial regeneration, stem cell dynamics, and differentiation. It is valuable for assessing how APC germline mutations affect cellular behavior before tumorigenic transformation. The organoid also supports research into inflammation, microbial interactions, and drug responses in genetically susceptible but phenotypically normal tissue—providing insights into early events in colorectal cancer development.