Human iPSC-Derived Mature Cerebral Organoid 100 days+
Human iPSC-derived cerebral organoid (100 days and older) are differentiated from iPSCs. As a three-dimensional in vitro model, cerebral organoids effectively replicate the cellular composition and structural organization of layers II through VI of the human cerebral cortex. They highly express a variety of neuronal types, including glutamatergic, GABAergic, and dopaminergic neurons, as well as glial cells such as oligodendrocytes and astrocytes. They are valuable for modeling neurodegenerative processes, including responses to PFF-induced toxicity, and can be used to study neurodegenerative diseases and Alzheimer's disease. Organoids are rigorously tested for mycoplasma, bacteria, fungi/yeast, and verified for identity, genetic stability, and functional performance.
Specifications
- cat no
- C-030
- disease
- Normal
- organism
- Human
- tissue
- Cerebral
- growth properties
- Embedded 3D Culture
- biosafety level
- 1
- growth conditions
- 37℃, 95% Air, 5% CO 2
- size quantity
- 1
- product format
- Frozen
- shipping info
- Dry Ice
- storage conditions
- Liquid Nitrogen
- quality control
- All test negative for mycoplasma, bacteria, yeast, and fungi.
- application
- For research use only. iPSC-derived organoids are used in various research fields, including disease modeling, drug discovery, gene therapy evaluation, and personalized medicine. They can replicate diverse disease states, providing reliable platforms for studying neurodegenerative diseases, cancer and more. Additionally, organoids are valuable for drug efficacy and safety testing, tissue regeneration studies, and exploring host-microbe interactions, advancing innovation in biomedical research.