Recombinant Human Basic FGF/FGF2 Protein, Tag-Free
Recombinant Human basic FGF/FGF2 Protein, Tag-Free is a member of the fibroblast growth factor family involved in bone healing, cartilage repair, bone regeneration, and nerve regeneration. FGF-2 also acts as a mitotic promoter, accelerating cell proliferation. It regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For instance, FGF-2 participates in the JAK-STAT signaling pathway to regulate cartilage metabolism and activates the ERK signaling pathway to promote cartilage regeneration. Additionally, FGF-2 in combination with FGFR1/3 promotes both the degeneration and repair of articular cartilage. FGF-2 is also a known carcinogen in GBM (glioblastoma multiforme), contributing to glioma growth and vascularization.
Specifications
- cat no
- R-076
- shipping info
- Ice
- application
- For research use only.
- product type
- Growth factor
- product description
- Recombinant Human basic FGF/FGF2 Protein, Tag-Free is a member of the fibroblast growth factor family involved in bone healing, cartilage repair, bone regeneration, and nerve regeneration. FGF-2 also acts as a mitotic promoter, accelerating cell proliferation. It regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For instance, FGF-2 participates in the JAK-STAT signaling pathway to regulate cartilage metabolism and activates the ERK signaling pathway to promote cartilage regeneration. Additionally, FGF-2 in combination with FGFR1/3 promotes both the degeneration and repair of articular cartilage. FGF-2 is also a known carcinogen in GBM (glioblastoma multiforme), contributing to glioma growth and vascularization.
- endotoxin level
- Less than 10 EU per mg protein.
- sterility
- Negative
- stability and storage
- Store frozen at -20 °C (short-term) or -80°C (long-term)
- molecular weight
- 16.5 kDa
- mycoplasma
- Negative
- purity
- ≥ 97 % as determined by SDS-PAGE
- expression system
- Human 293 cells (HEK293)
- formulation
- Lyophilized from sterile PBS, pH7.4, with 5% - 8% trehalose, mannitol, and 0.01% Tween80 as protectants.
- reconstitution
- Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.