R-092
Recombinant Human DKK-1 Protein, hFc Tag
Recombinant Human DKK-1 Protein, hFc Tag is a Wnt antagonist that binds LRP5/6 to inhibit canonical Wnt signaling. In organoid systems, DKK‑1 is used to control Wnt gradients in intestinal, gastric, and tumor organoids, and to study epithelial differentiation. Fc fusion provides stability and extended activity, making it useful in long‑term culture experiments. Produced at high purity for consistent Wnt modulation.
Specifications
- cat no
- R-092
- shipping info
- Ice
- application
- For research use only.
- product type
- Growth factor
- product description
- Recombinant Human DKK-1 Protein, hFc Tag is a Wnt antagonist that binds LRP5/6 to inhibit canonical Wnt signaling. In organoid systems, DKK‑1 is used to control Wnt gradients in intestinal, gastric, and tumor organoids, and to study epithelial differentiation. Fc fusion provides stability and extended activity, making it useful in long‑term culture experiments. Produced at high purity for consistent Wnt modulation.
- endotoxin level
- Less than 1.0 EU per μg by the LAL method.
- sterility
- Negative
- stability and storage
- Store frozen at -20 °C (short-term) or -80°C (long-term)
- molecular weight
- 52.5 kDa
- mycoplasma
- Negative
- purity
- ≥ 95 % as determined by SDS-PAGE; ≥ 95 % as determined by SEC-HPLC
- expression system
- Human 293 cells (HEK293)
- formulation
- Lyophilized from sterile PBS, pH7.4, with 5% - 8% trehalose, mannitol, and 0.01% Tween80 as protectants.
- reconstitution
- Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.