R-064
Recombinant Human FGF-4 Protein, Tag-Free
Recombinant Human FGF-4 Protein, Tag-Free is a developmental FGF used in organoid protocols to generate and mature stomach, lung, and liver organoids. FGF-4 Protein is a critical member of the fibroblast growth factor (FGF) family. By interacting with FGFRs, particularly FGFR1 and FGFR2, FGF-4 activates several downstream signaling cascades, including the RAS-MAPK and PI3K-AKT pathways. This protein plays a crucial role in various physiological processes, such as regulating cell growth, promoting differentiation, supporting cell migration, and driving angiogenesis.
Specifications
- cat no
- R-064
- shipping info
- Ice
- application
- For research use only.
- product type
- Growth factor
- product description
- Recombinant Human FGF-4 Protein, Tag-Free is a developmental FGF used in organoid protocols to generate and mature stomach, lung, and liver organoids. FGF-4 Protein is a critical member of the fibroblast growth factor (FGF) family. By interacting with FGFRs, particularly FGFR1 and FGFR2, FGF-4 activates several downstream signaling cascades, including the RAS-MAPK and PI3K-AKT pathways. This protein plays a crucial role in various physiological processes, such as regulating cell growth, promoting differentiation, supporting cell migration, and driving angiogenesis.
- endotoxin level
- Less than 0.1 EU per μg by the LAL method / rFC method.
- sterility
- Negative
- stability and storage
- Store frozen at -20 °C (short-term) or -80°C (long-term)
- molecular weight
- 14.0 kDa
- mycoplasma
- Negative
- purity
- >98%, as determined by SDS-PAGE quantitative densitometry
- expression system
- E. coli cells
- formulation
- Lyophilized from HEPES, NaCl, mannitol
- reconstitution
- Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.