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R-051

Recombinant Human GDNF Protein, Tag-Free

Recombinant Human GDNF Protein, Tag-Free is a highly purified, untagged version of Glial Cell Line-Derived Neurotrophic Factor (GDNF), produced for use in advanced organoid culture systems. GDNF is a potent neurotrophic factor that supports the survival, differentiation, and maturation of dopaminergic neurons, making it essential for organoid models involving neuronal development and neurodegeneration. In organoid research, particularly for dopaminergic neuron-based models, this tag-free version allows for more natural receptor interactions and provides more authentic signaling pathways. This protein is ideal for studying neuronal differentiation, neuroprotection, and the effects of GDNF on organoid morphology and function.

Specifications

cat no
R-051
shipping info
Ice
application
For research use only.
product type
Growth factor
product description
Recombinant Human GDNF Protein, Tag-Free is a highly purified, untagged version of Glial Cell Line-Derived Neurotrophic Factor (GDNF), produced for use in advanced organoid culture systems. GDNF is a potent neurotrophic factor that supports the survival, differentiation, and maturation of dopaminergic neurons, making it essential for organoid models involving neuronal development and neurodegeneration. In organoid research, particularly for dopaminergic neuron-based models, this tag-free version allows for more natural receptor interactions and provides more authentic signaling pathways. This protein is ideal for studying neuronal differentiation, neuroprotection, and the effects of GDNF on organoid morphology and function.
endotoxin level
Less than 0.01 EU per μg by the LAL method / rFC method.
sterility
Negative
stability and storage
Store frozen at -20 °C (short-term) or -80°C (long-term)
molecular weight
15.2 kDa
mycoplasma
Negative
purity
≥ 95% as determined by SDS-PAGE
expression system
Human 293 cells (HEK293)
formulation
Lyophilized from 0.22 μm filtered solution in 20 mM Sodium Citrate, 150 mM NaCl, pH4.0 with trehalose as protectant.
reconstitution
Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.