R-099
Recombinant Human Noggin/NOG Protein , hFc Tag
Recombinant Human Noggin/NOG Protein , hFc Tag is a BMP antagonist fused to Fc for stability and extended activity. In organoid media, it is essential with R‑spondin and EGF for intestinal organoids, and also supports cerebral, kidney, and prostate organoids. Fc fusion prolongs bioactivity, reducing feeding frequency. Validated to reproducibly inhibit BMP signaling in 3D systems.
Specifications
- cat no
- R-099
- shipping info
- Ice
- application
- For research use only.
- product type
- Growth factor
- product description
- Recombinant Human Noggin/NOG Protein , hFc Tag is a BMP antagonist fused to Fc for stability and extended activity. In organoid media, it is essential with R‑spondin and EGF for intestinal organoids, and also supports cerebral, kidney, and prostate organoids. Fc fusion prolongs bioactivity, reducing feeding frequency. Validated to reproducibly inhibit BMP signaling in 3D systems.
- endotoxin level
- Less than 1.0 EU per μg by the LAL method.
- sterility
- Negative
- stability and storage
- Store frozen at -20 °C (short-term) or -80°C (long-term)
- molecular weight
- 49.8 kDa
- mycoplasma
- Negative
- purity
- ≥ 95 % as determined by SDS-PAGE
- expression system
- Human 293 cells (HEK293)
- formulation
- Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, 50 mM Tris, pH 7.5 with 5% - 8% trehalose, mannitol, and 0.01% Tween80 as protectants.
- reconstitution
- Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.