R-006
Recombinant Human Noggin Protein, Fc Tag
Recombinant Human Noggin Protein, Fc Tag is a recombinant BMP inhibitor fused with an Fc domain for enhanced stability and solubility. This protein is critical in organoid models where BMP inhibition is required, including intestinal, cerebral, kidney, and lung systems. By blocking BMP signaling, Noggin promotes stem cell maintenance and controlled lineage development. The Fc fusion tag supports extended activity and improved handling, ensuring reliable use in long-term organoid cultures and advanced developmental biology applications.
Specifications
- cat no
- R-006
- shipping info
- Ice
- application
- For research use only.
- product type
- Growth factor
- product description
- Recombinant Human Noggin Protein, Fc Tag is a recombinant BMP inhibitor fused with an Fc domain for enhanced stability and solubility. This protein is critical in organoid models where BMP inhibition is required, including intestinal, cerebral, kidney, and lung systems. By blocking BMP signaling, Noggin promotes stem cell maintenance and controlled lineage development. The Fc fusion tag supports extended activity and improved handling, ensuring reliable use in long-term organoid cultures and advanced developmental biology applications.
- endotoxin level
- Less than 0.1 EU per μg by the LAL method / rFC method.
- sterility
- Negative
- stability and storage
- Store frozen at -20 °C (short-term) or -80°C (long-term)
- molecular weight
- 49.5 kDa
- mycoplasma
- Negative
- purity
- ≥ 95% as determined by SDS-PAGE
- expression system
- Human 293 cells (HEK293)
- formulation
- Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
- reconstitution
- Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.