R-005
Recombinant Human Noggin Protein, Tag-Free
Recombinant Human Noggin Protein, Tag-Free is a high-purity BMP pathway antagonist that binds BMP ligands and prevents receptor activation. In organoid research, Noggin is indispensable for maintaining intestinal stem cell identity, promoting neural induction in brain and cerebral organoids, and supporting kidney, liver, and prostate organoid differentiation. By inhibiting BMP signaling, Noggin sustains pluripotency and proper lineage specification. Produced animal origin-free and validated for reproducibility, this protein ensures robust performance across developmental and organoid culture systems.
Specifications
- cat no
- R-005
- shipping info
- Ice
- application
- For research use only.
- product type
- Growth factor
- product description
- Recombinant Human Noggin Protein, Tag-Free is a high-purity BMP pathway antagonist that binds BMP ligands and prevents receptor activation. In organoid research, Noggin is indispensable for maintaining intestinal stem cell identity, promoting neural induction in brain and cerebral organoids, and supporting kidney, liver, and prostate organoid differentiation. By inhibiting BMP signaling, Noggin sustains pluripotency and proper lineage specification. Produced animal origin-free and validated for reproducibility, this protein ensures robust performance across developmental and organoid culture systems.
- endotoxin level
- Less than 0.1 EU per μg by the LAL method / rFC method.
- sterility
- Negative
- stability and storage
- Store frozen at -20 °C (short-term) or -80°C (long-term)
- molecular weight
- 46.0 kDa
- mycoplasma
- Negative
- purity
- >98%, as determined by SDS-PAGE quantitative densitometry
- expression system
- E. coli cells
- formulation
- Resuspend in 10 mM HCl at > 50 µg/ml. Add carrier protein if desired. Prepare single-use aliquots.
- reconstitution
- Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.