R-070
Recombinant Human Noggin Protein, Tag-Free
Recombinant Human Noggin Protein, Tag-Free is a BMP antagonist that binds BMP2/4/7 to block receptor engagement and downstream SMAD signaling. Essential in intestinal organoids (with R‑spondin + EGF) to maintain LGR5+ stem cells; promotes neural induction in cerebral organoids; supports kidney, prostate, and gastric models requiring BMP inhibition. Enables controlled lineage specification alongside Wnt/TGF‑β cues. Produced animal‑origin‑free for reproducible organoid maintenance.
Specifications
- cat no
- R-070
- shipping info
- Ice
- application
- For research use only.
- product type
- Growth factor
- product description
- Recombinant Human Noggin Protein, Tag-Free is a BMP antagonist that binds BMP2/4/7 to block receptor engagement and downstream SMAD signaling. Essential in intestinal organoids (with R‑spondin + EGF) to maintain LGR5+ stem cells; promotes neural induction in cerebral organoids; supports kidney, prostate, and gastric models requiring BMP inhibition. Enables controlled lineage specification alongside Wnt/TGF‑β cues. Produced animal‑origin‑free for reproducible organoid maintenance.
- endotoxin level
- Less than 0.1 EU per μg by the LAL method / rFC method.
- sterility
- Negative
- stability and storage
- Store frozen at -20 °C (short-term) or -80°C (long-term)
- molecular weight
- 46.0 kDa
- mycoplasma
- Negative
- purity
- >98%, as determined by SDS-PAGE quantitative densitometry
- expression system
- E. coli cells
- formulation
- Lyophilized from acetonitrile and TFA with trehalose and other protectants as needed.
- reconstitution
- Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.