R-010
Recombinant Human R-spondin 1 LR5 Protein, Tag-Free
Recombinant Human R-spondin 1 LR5 Protein, Tag-Free is an engineered variant with enhanced potency for Wnt/β-catenin pathway activation. Compared with wild-type R-Spondin 1, this version provides stronger stimulation of epithelial stem cells, enabling more robust and sustained organoid expansion. It is particularly effective in intestinal and gastric models, where long-term growth and genetic stability are required. This protein supports high-efficiency organoid culture and Wnt pathway mechanistic studies.
Specifications
- cat no
- R-010
- shipping info
- Ice
- application
- For research use only.
- product type
- Growth factor
- product description
- Recombinant Human R-spondin 1 LR5 Protein, Tag-Free is an engineered variant with enhanced potency for Wnt/β-catenin pathway activation. Compared with wild-type R-Spondin 1, this version provides stronger stimulation of epithelial stem cells, enabling more robust and sustained organoid expansion. It is particularly effective in intestinal and gastric models, where long-term growth and genetic stability are required. This protein supports high-efficiency organoid culture and Wnt pathway mechanistic studies.
- endotoxin level
- Less than 0.1 EU per μg by the LAL method / rFC method.
- sterility
- Negative
- stability and storage
- Store frozen at -20 °C (short-term) or -80°C (long-term)
- molecular weight
- 13.0 kDa
- mycoplasma
- Negative
- purity
- ≥ 98%, as determined by SDS-PAGE quantitative densitometry
- expression system
- E. coli cells
- formulation
- Resuspend in 10 mM HCl at > 50 µg/ml. Add carrier protein if desired. Prepare single-use aliquots.
- reconstitution
- Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.