R-003
Recombinant Mouse EGF Protein, Fc Tag
Recombinant Mouse EGF Protein, Fc Tag is a recombinant epidermal growth factor fused to an Fc domain for enhanced stability and prolonged half-life. EGF binds EGFR and activates MAPK and PI3K/AKT pathways to drive epithelial cell proliferation, differentiation, and survival. In organoid systems, EGF is essential for maintaining and expanding epithelial tissues, particularly in intestinal, gastric, and lung organoids. The Fc fusion provides extended activity, making it highly suitable for long-term culture, receptor-binding studies, and translational epithelial biology models.
Specifications
- cat no
- R-003
- shipping info
- Ice
- application
- For research use only.
- product type
- Growth factor
- product description
- Recombinant Mouse EGF Protein, Fc Tag is a recombinant epidermal growth factor fused to an Fc domain for enhanced stability and prolonged half-life. EGF binds EGFR and activates MAPK and PI3K/AKT pathways to drive epithelial cell proliferation, differentiation, and survival. In organoid systems, EGF is essential for maintaining and expanding epithelial tissues, particularly in intestinal, gastric, and lung organoids. The Fc fusion provides extended activity, making it highly suitable for long-term culture, receptor-binding studies, and translational epithelial biology models.
- endotoxin level
- Less than 1.0 EU per μg by the LAL method / rFC method.
- sterility
- Negative
- stability and storage
- Store frozen at -20 °C (short-term) or -80°C (long-term)
- molecular weight
- 32.5 kDa
- mycoplasma
- Negative
- purity
- ≥ 95% as determined by SDS-PAGE
- expression system
- Human 293 cells (HEK293)
- formulation
- Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
- reconstitution
- Please refer to the Certificate of Analysis (CoA) for specific reconstitution instructions.